Alpha-1-Antitrypsin Quantitation

Last Modified: 8/13/2020 2:52:32 PM


Medical Necessity Documentation:  
Client Notes:  
Patient Preparation:  
Specimen Requirements: 1.0 mL Serum from a Red Top Tube in a Plastic Vial
Collection Instructions:  
Minimum Volume: 0.5 mL Serum
Transport & Storage: Temperature/Stability: 7 days Ambient
7 days Refrigerated
90 days Frozen
Reference Range: 83-199 mg/dL
Critical Ranges:  
Test Comments:  
Methodology: Immunoturbidimetric Assay
Clinical Significance:  Alpha-1-Antitrypsin level may be increased in normal pregnancy and in several diseases including chronic pulmonary disease; hereditary angioedema; renal, gastric, liver and pancreatic diseases; diabetes; carcinomas and rheumatoid diseases. Alpha-1-Antitrypsin may be decreased in emphysema, hepatic cirrhosis, respiratory distress syndrome of the newborn, nephrosis, malnutrition and cachexia. If a deficiency is present, aat phenotyping may be considered to confirm heterozygous versus homozygous deficiencies.
Documentation:  
Custom Panel: No

PRODUCTION SCHEDULE

Turn Around Time: 2 to 3 days
Days Performed: Monday, Tuesday, Wednesday, Thursday, Friday, Saturday
PHL Test Code: AAT1
Send Out Test Code: 235
Included Tests:  
CPT Coding: 82103

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