Beta-2 Transferrin

Last Modified: 8/31/2023 3:18:09 PM


Medical Necessity Documentation:  
Client Notes:  
Patient Preparation:  
Specimen Requirements: 0.5 mL Fluid in a sterile vial
Collection Instructions: Order must include the site and/or source of collection 

Example: Nasal, otic, or other fluids

 

-If direct collection is not feasible, specimen may be collected using plain cotton swab and submitted in a sterile, plastic leak-proof transport tube.

-If submitting syrine, remove needle and cap the syringe to avoid specimen leakage.

 

-Specimens contaminated with salivary fluid degrade the beta-2 transferrin.  These specimens should be frozen immediately following collection and should be kept frozen until testing is performed.

-Do not collect specimen with a culture swab.

-Do not add any liquid to the swab.
Minimum Volume: 0.2 mL Fluid
Transport & Storage: Temperature/Stability: 15 days Ambient
30 days Refrigerated (transport)
60 days Frozen
Rejection Criteria: Specimens collected with additives yield uninterpretable results and will be rejected; Cerebrial Spinal Fluid (CSF)
Reference Range:

Not detected
Critical Ranges:  
Test Comments:  
Methodology: Electrophoresis • Immunofixation
Clinical Significance: The presence of Beta-2 Transferrin in nasal or ear fluid, or in wound drainage following head trauma, surgery or from tumors or congenital malformation, clearly indicates CSF leaking into these passages or fluids creating a pathway for life-threatening central nervous system infection.
Documentation:
Custom Panel: No

PRODUCTION SCHEDULE

Turn Around Time: 2 to 3 days
Days Performed: Sunday, Monday, Tuesday, Wednesday, Thursday, Friday, Saturday
Sites Performed: Quest - Chantilly
PHL Test Code: BET2T
EPIC Test Code: LAB3000
Send Out Test Code: 10640
Included Tests:  
CPT Coding: 86335

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