Factor VII Activity

Last Modified: 8/31/2023 3:17:23 PM


Medical Necessity Documentation:  
Client Notes:  
Patient Preparation:  
Specimen Requirements:

1.0 mL frozen platelet poor plasma from a Blue Top Tube - 3.2% Na Citrate in a Plastic Vial
Collection Instructions: Clinical history/reason for referral is required with test order.

Centrifuge light blue-top tube for 15 minutes at approximately 1500 g within 60 minutes of collection. Using a plastic pipette, remove plasma, taking care to avoid the WBC/platelet buffy layer and place into a plastic vial. Centrifuge a second time and transfer platelet-poor plasma into a new plastic vial. Plasma must be free of platelets (<10,000/mcl). Freeze immediately and ship on dry ice.
Minimum Volume: 0.5 mL Platelet Poor Plasma
Transport & Storage: Temperature/Stability: Unacceptable Ambient
Unacceptable Refrigerated
14 days Frozen(Transport)
Rejection Criteria: Hemolysis; Received Thawed; Ship at room temperature. Specimen viability decreases during transit. Send specimen to testing lab for viability determination. Do not freeze. Do not reject.
Reference Range: 60 -150% of normal
Critical Ranges:  
Test Comments:  
Methodology: Photometric Clot Dectection
Clinical Significance:

Limitations
Expected impact by therapeutic levels (potential interference depends upon drug concentration): Warfarin: decreased, Heparin (UFH or LMWH): no effect (reagent contains heparin neutralizer); Dabigatran or Argatroban (Thrombin Inhibitors): no effect to inhibitor pattern or falsely low; Rivaroxaban or Apixaban (Factor Xa Inhibitors): no effect to inhibitor pattern
Documentation:  
Custom Panel: No

PRODUCTION SCHEDULE

Turn Around Time: 4 to 7 days
Days Performed: Monday, Tuesday, Wednesday, Thursday, Friday
Sites Performed: Quest - Chantilly
PHL Test Code: FACT7
EPIC Test Code: LAB305
Send Out Test Code: 346X / 29193
Alternate Test Names: Facto VII Functional; Factor VII Assay; Proconvertin; Stable Factor
Included Tests:  
CPT Coding: 85230

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