Hepatitis C Viral RNA, Genotype

Overview

  • EPIC Code:
  • LAB915
  • Soft Test Code:
  • HSUB
  • Send Out Test Code:
  • 37811
Alternate Names
  • HCV Genotype, LiPA
  • HCV RNA Genotype, LIPA
  • HCV Viral RNA Genotype, LiPA
  • Hepatitis C Genotype
  • Hepatitis C Viral Genotype by LIPA
  • Hepatitis C Viral RNA, Genotype
  • Hepatitis C Viral RNA, Genotype, LiPA
Clinical Significance

Determination of hepatitis C genotype is often required to select the most appropriate direct acting agent(s) (DAA) for the treatment of hepatitis C. Some DAA's are only effective for the treatment of hepatitis C genotype 1, whereas others may be used for additional genotypes. Refer to the package inserts of the relevant DAA's for guidance. A concurrent patient HCV viral load of >=300 IU/mL is required for this test.


Specimen Collection & Preparation

Specimen Requirements:

-OR-

2.0 mL Plasma from a Lavender Top Tube - EDTA in a Plastic Vial
Minimum Volume:
0.6 mL Plasma*

* This volume does not allow for repeat testing

Processing Instructions:

Centrifuge at 800-1600 x g for 20 minutes at room temperature

Separate plasma within 24 hours of collection

Transfer the plasma to a properly identified, sterile, polypropylene screw-cap vial


Rejection Criteria:

Unspun specimen

Specimen on cells for >24 hours

Heparinized samples


Transport and Storage:
  • Ambient (18-24°C): 72 hours
  • Refrigerated (2-8°C): 14 days

    Transport in cold packs

  • Frozen (-20° C or colder): 42 days

Clinical Interpretation

Reference Range:

See Laboratory Report


Methodology:
  • Reverse Transcriptase Polymerase Chain Reaction (RT-PCR)
Clinical Significance

Determination of hepatitis C genotype is often required to select the most appropriate direct acting agent(s) (DAA) for the treatment of hepatitis C. Some DAA's are only effective for the treatment of hepatitis C genotype 1, whereas others may be used for additional genotypes. Refer to the package inserts of the relevant DAA's for guidance. A concurrent patient HCV viral load of >=300 IU/mL is required for this test.


Production Schedule

Sites Performed
  • Quest - Chantilly
Days Performed
Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Departments
  • Sendouts - Clinical
Turn Around Time

2 to 5 days


Coding & Compliance

CDM

00917109


CPT Coding

87902