Human Growth Hormone

Last Modified: 3/27/2019 2:56:42 PM

Medical Necessity Documentation:  
Client Notes:  
Patient Preparation:  
Specimen Requirements: 1.0 mL Serum from a Red Top Tube in a Plastic Vial
Collection Instructions:  
Minimum Volume: 0.5 mL
Transport & Storage: Temperature/Stability: 7 days Ambient
7 days Refrigerated
28 days Frozen
Reference Range: Because of a pulsatile secretion pattern, random (unstimulated) growth hormone (GH) levels are frequently undetectable in normal children and adults and are not reliable for diagnosing GH deficiency. Regarding suppression tests, failure to suppress GH is diagnostic of acromegaly.

Typical GH response in healthy subjects: 
Using the Glucose Tolerance (GH Suppression) test, acromegaly is ruled out if the patient's GH level is < 1.0 ng/mL at any point in the timed sequence.

Using the GH Stimulation test, the following result at any point in the sequence rules out GH deficiency: 

Pediatric (< 20 years): All stimulation tests > or = 10.0 ng/mL

Adults (> or = 20 years): < or = 7.1 ng/mL

Critical Ranges:  
Test Comments:  
Methodology: Immunoassay
Clinical Significance: Measurement of GH is primarily used for the diagnosis and treatment of disorders of growth hormone secretion, including GH excess (acromegaly) and deficiency. Growth hormone measurements in children are used in the evaluation of short stature and help differentiate short stature, due to low GH production from other causes of growth failure.
Custom Panel: No


Turn Around Time: 3 to 5 days
Days Performed: Monday, Tuesday, Wednesday, Thursday, Friday
Sites Performed: Quest - Chantilly
PHL Test Code: HGH
EPIC Test Code: LAB525
Send Out Test Code: 521
Alternate Test Names: Growth Hormone (GH); HGH
Included Tests:  
CPT Coding: 83003

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