Last Modified:
3/25/2019 2:48:05 PM
Medical Necessity Documentation:
Client Notes:
Patient Preparation:
Specimen Requirements:
1.5 mL Serum from a Red Top Tube in a Plastic Vial
Collection Instructions:
The Informational Form MUST be filled out completely and submitted with specimen
Minimum Volume:
0.8 mL
Transport & Storage: Temperature/Stability:
7 days Ambient
7 days Refrigerated
60 days Frozen
Reference Range:
| MSS Down Syndrome Risk |
<1:270 |
| MSS Risk for Trisomy 18 Risk |
<1:100 |
Critical Ranges:
Test Comments:
This test was developed and its performance characteristics have been determined by Quest Diagnostics. Performance characteristics refer to the analytical performance of the test.
Methodology:
Chemiluminescence (CL) • Immunoassay (IA)
Clinical Significance:
To screen for Down syndrome and trisomy 18 at 9.0-13.9 weeks gestation
Documentation:
Limitations: First Trimester Screen results consistent with increased risk of trisomy should be confirmed with CVS or amniotic fluid specimen. Maternal serum screening yields a low percentage of false negatives. A wide range of other chromosomal abnormalities are not identified by maternal serum screening
Research Test Only
Custom Panel:
No
PRODUCTION SCHEDULE
Turn Around Time:
3 to 5 days
Days Performed:
Monday, Tuesday, Wednesday, Thursday, Friday, Saturday
Sites Performed:
Quest - Chantilly
PHL Test Code:
FTSOH
EPIC Test Code:
LAB2883
Send Out Test Code:
16020
Alternate Test Names:
1st Trimester,Down Syndrome and Trisomy 18 Screen; h-hCG; Hyperglycosylated hCG (h-hCG); Invasive Trophoblast Antigen (ITA); MSS; Nuchal Translucency (NT); Pregnancy-associated Plasma Protein-A (PAPP-A)
Included Tests:
h-hCG (hyperglycosylated hCG); PAPP-A (Pregnancy-associated Plasma Protein); risk calculation which includes NT (Nuchal Translucency)
CPT Coding:
84163, 82397
Go back to the top of the page.