Histoplasma Antibody (1)

Overview

  • EPIC Code:
  • IMO413
  • Soft Test Code:
  • HISTO
  • Send Out Test Code:
  • 938
Alternate Names
  • Histoplasma Antibody, CF
  • Histoplasma Antibody, Complement Fixation
  • Histoplasma Antibody, Complement Fixation, Serum
  • Histoplasma Mycelial Yeast
Included Tests

Mycelial Phase Antibody; Yeast Phase Antibody; 


Clinical Significance

 Histoplasma Antibody, Complement Fixation, Serum - This test is used for the diagnosis and prognosis of histoplasma infections.
Titers ≥1:32 are highly suggestive of H. capsulatum infection. The CF test is more frequently positive with sera from chronic active pulmonary histoplasmosis than sera from primary active pulmonary disease.


Specimen Collection & Preparation

Specimen Requirements

1.0 mL Serum in a SST Gold Top Tube


Transport And Storage

7 days Ambient
14 days Refrigerated (Preferred)
30 days Frozen

 Avoid Thaw/Freeze Cycles


Collection Instructions

Centrifuge and separate from cells within one hour of collection


Minimum Volume

0.5 mL


Neonatal Volume

Clinical Interpretation

Reference Range:

Yeast Phase Ab <1:8
Mycelial Phase Ab <1:8


Test Comments:

Clinical interpretation of complement fixation test results requires comparison of an acute serum sample to a convalescent serum sample. The convalescent serum sample should be collected 2-3 weeks later.


Methodology:
  • Complement Fixation (CF)
Clinical Significance

 Histoplasma Antibody, Complement Fixation, Serum - This test is used for the diagnosis and prognosis of histoplasma infections.
Titers ≥1:32 are highly suggestive of H. capsulatum infection. The CF test is more frequently positive with sera from chronic active pulmonary histoplasmosis than sera from primary active pulmonary disease.


Production Schedule

Sites Performed
  • Quest - Chantilly
Days Performed
Tuesday
Wednesday
Thursday
Friday
Departments
  • Sendouts - Clinical
Turn Around Time

2 to 5 days


Coding & Compliance

CPT Coding

86698 x 2