Histoplasma Antibody

Last Modified: 8/12/2021 5:41:23 AM

Medical Necessity Documentation:  
Client Notes:
Patient Preparation:  
Specimen Requirements:

1.0 mL Serum in a SST Gold Top Tube

Collection Instructions: Centrifuge and separate from cells within one hour of collection
Minimum Volume: 0.5 mL
Transport & Storage: Temperature/Stability: 7 days Ambient
14 days Refrigerated (Preferred)
30 days Frozen

 Avoid Thaw/Freeze Cycles
Rejection Criteria: Gross hemolysis; grossly icteric; grossly lipemic
Reference Range:
Yeast Phase Ab <1:8
Mycelial Phase Ab <1:8
Critical Ranges:  
Test Comments: Clinical interpretation of complement fixation test results requires comparison of an acute serum sample to a convalescent serum sample. The convalescent serum sample should be collected 2-3 weeks later.
Methodology: Complement Fixation
Clinical Significance:  Histoplasma Antibody, Complement Fixation, Serum - This test is used for the diagnosis and prognosis of histoplasma infections.
Titers ≥1:32 are highly suggestive of H. capsulatum infection. The CF test is more frequently positive with sera from chronic active pulmonary histoplasmosis than sera from primary active pulmonary disease.
Custom Panel: No


Turn Around Time: 2 to 5 days
Days Performed: Tuesday, Wednesday, Thursday, Friday
Sites Performed: Quest - Chantilly
PHL Test Code: HISTO
EPIC Test Code: IMO413
Send Out Test Code: 938
Alternate Test Names: Histoplasma Antibody, CF; Histoplasma Antibody, Complement Fixation; Histoplasma Antibody, Complement Fixation, Serum; Histoplasma Mycelial Yeast
Included Tests: Mycelial Phase Antibody; Yeast Phase Antibody; 
CPT Coding: 86698 x 2

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