Parkview Laboratory: Test Directory
Home
Test Directory
About Us
Mission & Vision Statements
Medical Directors and Technical Consultants
Administrators
Certification and Accreditation Information
Laboratory Locations
Patient Information
Where can I get my blood drawn?
Pay your Bill, Get a Price Estimate, Is Parkview In Network
My Chart - Get Access / Get Lab Results
On My Way
Patient Collection Instructional Sheets
What is Direct Access Testing and is it right for you
Lab Links
Parkview Health
External Lab Resource
PHL Clients
MEDICARE NUMBER AND CARD CHANGES
Inappropriate Duplicate Testing
Flow Cytometry Ordering Guidelines
Certification and Accreditation Information
Cytology Collection Information
Histology Collection Information
Specimen Collection and Handling Requirements
Microbiology Specimen Collection, Rejection and Safety Information
Specimen Types, Descriptions, and Definitions
Billing (Insurance/Account/Patient/Medicare) Definitions and Information
Customer Service
How to use this Online Directory
Physicians Quick Reference for Medicare Preventive Services
View Medical Necessity Guide
View Stat Eligible Testing Report
Extractable Nuclear Antigen Antibodies
Last Modified:
4/20/2022 8:29:12 AM
Medical Necessity Documentation:
Client Notes:
Patient Preparation:
Specimen Requirements:
1.0 mL Serum in a SST
Gold Top Tube
Collection Instructions:
Minimum Volume:
0.5 mL
Transport & Storage: Temperature/Stability:
8 hrs Ambient
2 days Refrigerated
28 days Frozen
Do not use frost free units that undergo repeated freeze/thaw cycles
Do not transport Frozen.
Specimen to be transported Refrigerated to PRMC within 48 hours of collection to be frozen by Immunology department to maintain specimen integrity until testing occurs.
Reference Range:
Smith Antibody
< 1.0 AI Negative
Smith/Ribonucleoprotein Antibody
< 1.0 AI Negative
Critical Ranges:
Test Comments:
Methodology:
Enzyme Immunoassay
Clinical Significance:
Antibodies to Sm are highly specific for systemic lupus erythematosus (SLE) and, when present, are considered a marker antibody. However, these antibodies are found in only 20% of patients with SLE. RNP antibodies (also known as anti-u1 or ribonucleoprotein antibodies) are found in 45% of SLE patient, but are also observed in numerous other disease states such as Sjogren's syndrome, scleroderma, and polymyositis. Elevated levels of antibodies to RNP are seen in mixed connective tissue
disease. In SLE, RNP antibodies have been associated with a relatively benign disease course with lower incidence of renal and central nervous system involvement. Patients may be considered positive for RNP antibodies when the RNP antibody result is significantly higher than the Sm antibody result.
Documentation:
Custom Panel:
No
PRODUCTION SCHEDULE
Turn Around Time:
7 days
Days Performed:
Friday
Sites Performed:
Parkview Regional Medical Center
PHL Test Code:
ENAA1
EPIC Test Code:
IMO421
Alternate Test Names:
Anti ENA(SM/RNP)Antibodies; Anti-ENA; Anti-RNP; Anti-SM; ENA Antibodies; SM and SM/RNP Antibodies; Smith (SM) / Ribonucleoprotein (RNP) Antibody
Included Tests:
Sm (Smith) IgG Autoantibodies; RNP Antibodies
CPT Coding:
86235 x 2
Go back to the top of the page.