Cytomegalovirus IgG Avidity

Last Modified: 2/15/2019 7:19:34 AM


Specimen Requirements: 0.5 mL Serum from a Red Top Tube in a Plastic Vial
Collection Instructions: Centrifuge and separate from cells immediately
Minimum Volume: 0.25 mL Serum
Transport & Storage: Temperature/Stability: 7 days Ambient (Transport)
14 days Refrigerated
30 days Frozen
Reference Range: ≥0.60
Methodology: Immunoassay
Clinical Significance: Discrimination between recent (primary) and past cytomegalovirus (CMV) infection can be an important tool in the clinical management of transplant recipients and pregnant women. Although nearly all individuals with recent CMV infection are positive for CMV IgM, individuals with past CMV may also express CMV IgM, following viral reactivation; thus, detection of CMV IgM is not a reliable indicator of recent infection. Measurement of CMV IgG avidity can assist in discriminating recent from past CMV infection. Although a low avidity index is a reliable indicator of CMV infection within the previous 6 months, a high avidity index is more meaningful from a clinical standpoint; a high avidity index essentially excludes the possibility that infection occurred within the previous 4 months
Documentation: Laboratory Developed Test at Focus Diagnostics, Inc.
Custom Panel: No

PRODUCTION SCHEDULE

Turn Around Time: 1 to 3 days
Days Performed: Sunday, Tuesday, Wednesday, Thursday, Friday
Sites Performed: Quest Diagnostic Infectious Disease
PHL Test Code: MSOT
EPIC Test Code:
Send Out Test Code: 19583
Alternate Test Names: CMV IgG Avidity; Cytomegalovirus (CMV) IgG Avidity (AviDx), ELISA
CPT Coding: 86644

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