Aldosterone/Plasma Renin Activity Ratio, LC/MS/MS

Last Modified: 8/31/2023 3:15:10 PM


Medical Necessity Documentation:  
Client Notes:  
Patient Preparation:  
Specimen Requirements: 1.8 mL Frozen Plasma from a Lavender Top Tube - EDTA in a Plastic Vial
Collection Instructions: Centrifuge and transfer plasma to separate plastic vial and freeze
Minimum Volume: 0.8 mL Plasma
Transport & Storage: Temperature/Stability:

28 days Frozen
Rejection Criteria: Plasma collected in plasma separator tube (PST); moderate to gross hemolysis; received thawed
Reference Range:

Aldosterone

Adult    
Upright 8:00-10:00 A.M. ≤28 ng/dL
Upright 4:00-6:00 P.M. ≤21 ng/dL
Supine 8:00-10:00 A.M. 3-16 ng/dL
Pediatric    
1-12 Months 2-70 ng/dL
1-4 Years 2-37 ng/dL
5-9 Years ≤9 ng/dL
10-13 Years ≤21 ng/dL
14-17 Years ≤35 ng/dL
Infants    
Premature (31-35 Weeks) ≤144 ng/dL
Term ≤217 ng/dL
Tanner Stages    
II-III Males 1-13 ng/dL
II-III Females 2-20 ng/dL
IV-V Males 3-14 ng/dL
IV-V Females 4-32 ng/dL

Plasma Renin Activity 0.25-5.82 ng/mL/h
Aldosterone/PRA Ratio 0.9-28.9 Ratio

Critical Ranges:  
Test Comments:  
Methodology: Liquid Chromatography Tandem Mass Spectrometry (LC/MS/MS)
Clinical Significance: The Aldosterone-renin ratio is used to screen for primary aldosteronism
Documentation:  
Custom Panel: No

PRODUCTION SCHEDULE

Turn Around Time: 5 to 7 days
Days Performed: Sunday, Monday, Tuesday, Wednesday, Thursday, Friday
Sites Performed: Quest - Chantilly
PHL Test Code: ALDR
EPIC Test Code: LAB3002
Send Out Test Code: 16845
Alternate Test Names: Aldosterone/Plasma Renin Activity Ratio, LC/MS/MS
Included Tests: Aldosterone, Plasma Renin Activity; Aldosterone/Plasma Renin Activity Ratio
CPT Coding: 82088, 84244

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