JAK2, Exon 12 Mutation Analysis

Clinical Significance

This DNA-based assay tests leukocytes from blood or bone marrow aspirate for mutations in exon 12 of JAK2, using an advanced DNA sequencing method. These mutations are associated with myeloproliferative neoplasms, particularly polycythemia vera.

Specimen Requirements

5.0 mL Whole Blood in a Lavender Top Tube - EDTA

Transport And Storage

7 days Ambient
7 days Refrigerated

Collection Instructions

 

Minimum Volume

3.0 mL Whole Blood EDTA

Neonatal Volume

Reference Range:

Refer to Interpretive Results

Methodology:

• DNA Sequencing
• Polymerase Chain Reaction (PCR)

Clinical Significance

This DNA-based assay tests leukocytes from blood or bone marrow aspirate for mutations in exon 12 of JAK2, using an advanced DNA sequencing method. These mutations are associated with myeloproliferative neoplasms, particularly polycythemia vera.

CDM

00918203

CPT Coding

81479