Platelet antibodies may be allo- or autoantibodies and may be directed to a wide range of antigenic "targets" carried on platelet cytoplasmic membranes. Serum platelet antibody test is optimized to identify the presence of platelet alloantibodies in the patient.
Platelet alloantibodies are involved in several clinical situations such as:
-Immune mediated refractoriness to platelet transfusions usually due to antibodies to class I human leukocyte antigens and sometimes to antibodies specific to platelet antigens.
-Neonatal alloimmune thrombocytopenia -Posttransfusion purpura, which are usually associated with platelet-specific antibodies
This test is not recommended for the diagnosis of immune thrombocytopenia or autoimmune thrombocytopenia. Tests that are optimized to detect antibodies bound to the platelets will be useful in these situations; cell-bound platelet antibody (direct) test is strongly recommended.
* This volume does not allow for repeat testing
Centrifuge and separate from cells prior to shipping
Gross hemolysis
Serum separator tube (SST)
Transport
See Separate Laboratory Report
Platelet antibodies may be allo- or autoantibodies and may be directed to a wide range of antigenic "targets" carried on platelet cytoplasmic membranes. Serum platelet antibody test is optimized to identify the presence of platelet alloantibodies in the patient.
Platelet alloantibodies are involved in several clinical situations such as:
-Immune mediated refractoriness to platelet transfusions usually due to antibodies to class I human leukocyte antigens and sometimes to antibodies specific to platelet antigens.
-Neonatal alloimmune thrombocytopenia -Posttransfusion purpura, which are usually associated with platelet-specific antibodies
This test is not recommended for the diagnosis of immune thrombocytopenia or autoimmune thrombocytopenia. Tests that are optimized to detect antibodies bound to the platelets will be useful in these situations; cell-bound platelet antibody (direct) test is strongly recommended.
2 to 4 days
00913333
86606 x 3