Bleeding Time

Last Modified: 8/31/2023 3:16:23 PM


Medical Necessity Documentation:  
Client Notes: Prior to your collection please contact PHL Client Response at 266-1500 (Option 2) to request a Stat courier to maintain the integrity and stability of the specimen. 

If specimen can not reach Parkview Regional Medical Center (PRMC) within 3 hours of collection, please send the patient to PRMC to be drawn at 11109 Parkview Plaza Entrance 3. 
Patient Preparation:  
Specimen Requirements: 5.4 mL Whole Blood in two (2) Blue Top Tubes - 3.2% Na Citrate
Collection Instructions: Collect this specimen with a 21G needle
Transport & Storage: Temperature/Stability: 4 hours Ambient "Specimen must be received at testing site within 3 hours of collection"
Rejection Criteria: Centrifuged; Refrigerated; Frozen
Reference Range:
Collagen/EPI: 69 - 173 Seconds 
Collagen/ADP: 54 - 126 Seconds
Critical Ranges:  
Test Comments: Collagen/EPI will always be performed. If Collagen/EPI is >173 sec, Collagen/ADP testing will be performed.

Methodology: Platelet Function Analyzer
Clinical Significance: Coll/EPI          Coll/ADP
< =173 sec     Not Done
Platelet Function appears adequate. The effects of ADP receptor blockers such as Clopidogrel are unpredictable.
Coll/EPI           Coll/ADP
>173 sec        <=126 sec
An Elevated Collagen/EPI result with a Normal/Low Collagen/ADP result is consistent with any of the following: mild thrombocytopenia, low hematocrit, mild platelet dysfunction, mild von Willebrand disease or may be related to recent antiplatelet medication including aspirin. The effects of ADP receptor blockers such as Clopidogrel are unpredictable.
 
 Coll/EPI            Coll/ADP
>173 sec         >126 sec
An Elevated Collagen/EPI with an Elevated Collagen/ADP result is consistent with any of the following or combination of: thrombocytopenia, low hematocrit, platelet dysfunction, von Willebrand disease or recent antiplatelet medication such as GPllb/llla receptor inhibitors. The effects of ADP receptor blockers such as Clopidogrel are unpredictable. Additional follow-up may be warranted if clinically indicated. 
Documentation:  
Custom Panel: No

PRODUCTION SCHEDULE

Stat Eligible: Yes
Days Performed: Sunday, Monday, Tuesday, Wednesday, Thursday, Friday, Saturday
Sites Performed: Parkview Regional Medical Center
PHL Test Code: BLED
EPIC Test Code: LAB333
Alternate Test Names: PFA 100; Platelet Function Assay 100
Included Tests:  
CPT Coding: 85576 (Reflex 85576)

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