JC Polyoma Virus DNA, Quantitative

Overview

  • EPIC Code:
  • MISC
  • Soft Test Code:
  • MSOT
  • Send Out Test Code:
  • 16442
Alternate Names
  • JC Polyoma Virus (JCV)
  • JC Polyoma Virus DNA, Quantitative, Real-Time PCR,
  • JC Virus, PCR (Polyoma) CSF
  • Polyoma
Clinical Significance

JC Polyoma Virus (JCV) is the cause of progressive multifocal leukoencephalopathy (PML), a demyelinating neurologic disease of immunosuppressed patients. This test detects JC Polyoma Virus DNA in CSF. Detection of the virus in specimens from AIDS and other severely immune compromised patients may indicate disease. Serum antibodies are not helpful in diagnosing PML as antibodies are common in the general population. JCV can also be detected in the urine of 3% of pregnant women, but is not associated with proven disease.


Specimen Collection & Preparation

Specimen Requirements

1.0 mL Frozen CSF in a Sterile Container


Transport And Storage

48 hours Ambient
7days Refrigerated
30 day Frozen


Collection Instructions

If multiple Fluid or CSF test are being requested please specify order of importance


Minimum Volume

0.3 mL CSF


Neonatal Volume

Clinical Interpretation

Reference Range:

JC Virus DNA, QN PCR CSF: Not Detected IU/mL
JC Virus DNA, QN PCR CSF: Not Detected log IU/mL


Methodology:
  • Real-Time Polymerase Chain Reaction
Clinical Significance

JC Polyoma Virus (JCV) is the cause of progressive multifocal leukoencephalopathy (PML), a demyelinating neurologic disease of immunosuppressed patients. This test detects JC Polyoma Virus DNA in CSF. Detection of the virus in specimens from AIDS and other severely immune compromised patients may indicate disease. Serum antibodies are not helpful in diagnosing PML as antibodies are common in the general population. JCV can also be detected in the urine of 3% of pregnant women, but is not associated with proven disease.


Production Schedule

Sites Performed
  • Quest - Chantilly
Days Performed
Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Departments
  • Sendouts - Miscellaneous
Turn Around Time

2 to 3 days


Coding & Compliance

CDM

00913333


CPT Coding

87799