Actin Antibody IgG

Last Modified: 2/13/2019 11:03:59 AM

Medical Necessity Documentation:  
Client Notes:  
Patient Preparation:  
Specimen Requirements:

0.5 mL Serum from a Red Top Tube in a Plastic Vial

Collection Instructions:  
Minimum Volume: 0.1 mL
Transport & Storage: Temperature/Stability: 8 hours Ambient
2 weeks Refrigerated
1 month Frozen
Reference Range: Negative: < 20 Units
Weak positive: 20-30 Units
High positive: > 30 Units
Critical Ranges:  
Test Comments:

This ELISA assay is based on purified F-Actin IgG antibodies. IgG antibodies to F-Actin are present in approximately 75% of patients with autoimmune hepatitis type 1, 65% with autoimmune cholangitis, 30% with primary biliary cirrhosis, and 2% of the healthy population.


Methodology: Enzyme-Linked Immunosorbent Assay
Clinical Significance:  
Custom Panel: No


Turn Around Time: 3 to 5 days
Days Performed: Monday, Tuesday, Wednesday, Thursday, Friday
Sites Performed: Quest - Chantilly
PHL Test Code: SMA1
EPIC Test Code: IMO206
Send Out Test Code: 15043 / 15043X
Alternate Test Names: ACTA; Anti-Smooth Muscle Antibody; ASMA; F-Actin Antibody; SM Muscle Actin Ab; SMA; Smooth Muscle Antibody
Included Tests:  
CPT Coding: 83516

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