HSP-70 Antibody

Last Modified: 7/18/2016 8:20:23 AM

Specimen Requirements:

1.0 mL Serum in a SST Gold Top Tube

Minimum Volume: 0.5 mL Serum
Transport & Storage: Temperature/Stability: 7 days Ambient
14 days Refigerated
21 day Frozen

Transport Ambient
Reference Range: Negative
Methodology: Western Blot
Clinical Significance: Sensorineural hearing loss (SNHL), commonly referred to as nerve deafness, may be caused by genetic or acquired factors, such as infections, or can be immunologically mediated. A subgroup of idiopathic SNHL cases are treatable with immunosuppressive therapy. The laboratory work up to identify these cases should include serum antibody tests to 68 kD inner ear antigen. Twenty-two percent of patients with bilateral rapidly progressive SNHL and 30% of the patients with Meniere's disease had antibodies that reacted with 68 kD antigen present in the bovine inner ear extracts. Anti-68kD antibodies also occur in approximately 60% of patients with bilateral and 35% of patients with unilateral Meniere's syndrome and 37% of patients with contralateral delayed endolymphatic hydrops.
Custom Panel: No


Turn Around Time: 6 to 9 days
Days Performed: Tuesday, Friday
Sites Performed: Quest - Chantilly to San Juan Capistrano
PHL Test Code: MSOT
EPIC Test Code:
Send Out Test Code: 36734
Alternate Test Names: 68 kd Ag; 68 kd Antigen; 68 Kilodalton Antigen; Anti-68 kd Antigen; Hearing Loss Ab; Heat Shock Protein 70; Meniere's Disease; Sensorineural Hearing Loss (SNHL)
CPT Coding: 84181

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