IgG Synthesis Rate/Index, CSF

Overview

  • EPIC Code:
  • Soft Test Code:
  • MSOT
  • Send Out Test Code:
  • 7558
Alternate Names
  • IgG Synthesis Rate
  • IgG Synthesis Rate, CNS Index
Included Tests

Albumin; Albumin CSF;  CSF IgG Index, CSF Synthesis Rate IgG; IgG Total; IgG CSF


Clinical Significance

The IgG Synthesis Rate/Index is useful in diagnosing and monitoring patients with multiple sclerosis and other inflammatory diseases involving the brain and meninges


Specimen Collection & Preparation

Specimen Requirements

2.0 CSF in a #4 CSF Collection Sterile Plastic Vial
and 
1.0 mL Serum from a Red Top Tube in a Plastic Vial


Transport And Storage

7 days Refrigerated
90 days Frozen

Refrigerated CSF at 2-8°C in sterile, plastic CSF vials, and send refrigerated (Cold Packs) to lab
or 
Freeze CSF specimens at -20°C and send frozen to the lab on dry ice


Collection Instructions

Serum and CSF samples should be drawn on same day for most reliable results

If multiple testing is required for the CSF specimen, please list the testing priorities on the order

It is preferred that the collection date and time be the same for both CSF and Serum; however it is acceptable for them to be drawn within 48 hours of each other. CSF must be crystalline and clear.

Blood contamination and hemolysis may interfere with results. Submitting 4th lumbar puncture collection tube minimizes blood contamination.


Minimum Volume

1.0 mL CSF & 0.5 mL Serum


Neonatal Volume

Clinical Interpretation

Reference Range:

Refer to Interpretive Results


Methodology:
  • Nephelometry
Clinical Significance

The IgG Synthesis Rate/Index is useful in diagnosing and monitoring patients with multiple sclerosis and other inflammatory diseases involving the brain and meninges


Production Schedule

Sites Performed
  • Quest - Chantilly
Days Performed
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Departments
  • Sendouts - Miscellaneous
Turn Around Time

1 to 2 days


Coding & Compliance

CDM

00913333


CPT Coding

82040, 82042, 82784 x 2