Adrenocorticotropic Hormone Stimulation Test

Last Modified: 12/4/2023 5:18:43 AM


Medical Necessity Documentation:  
Client Notes:

Synthetic ACTH Injections are performed at Parkview Randallia Hospital Infusion Center Only. 

Outpatients - To schedule please contact Parkview Infusion Center (2200 Randallia 2nd Floor) to schedule call 373-4585
Patient Preparation: Glucocorticoids should not be taken prior to an ACTH stimulation test.  The ordering provider will provide instructions to the patient detailing the length of time glucocorticoids should be withheld.  Questions about compliance with these instructions should be referred to the ordering provider.
Specimen Requirements:

1.0 mL Serum in a SST Gold Top Tube - One for each timed draw
Collection Instructions:
  1. A base line level Cortisol to be drawn.
  2. Within 30 minutes of baseline being drawn, the patient is to be given a 250-uG dose of synthetic ACTH, Cortrosyn, IM.
  3. A second Cortisol to be drawn one-half hour after this dose is given.
  4. A third Cortisol to be drawn one hour after the dose is given

Example:
1. Base Line Cortisol - 8:00 A.M.
2. ACTH Dose - 8:05 A.M. 
3. One-Half Hour Cortisol - 8:35 A.M 
4. One Hour Cortisol - 9:05 A.M.
 
Above is just an Example of time frames this testing can be started any time (not limited to 8am) 
Minimum Volume: 0.5 mL
Transport & Storage: Temperature/Stability: 48 hours Refrigerated
Reference Range:
No reference range established
Critical Ranges:  
Test Comments:
A normal increase of at least 7 UG/DL of Cortisol is expected for a short ACTH stimulation test.
Methodology: Chemiluminscence
Clinical Significance: Method for testing the adrenal reserve to rule out Addison Disease
Documentation:  
Custom Panel: No

PRODUCTION SCHEDULE

Days Performed: Sunday, Monday, Tuesday, Wednesday, Thursday, Friday, Saturday
Sites Performed: Parkview Regional Medical Center
PHL Test Code: ACTHS
EPIC Test Code: LAB711
Alternate Test Names: ACTH Short Stimulation Test ; ACTH Stimulation Test; Addison Disease Testing; Cortrosyn Stimulation; Cosyntropin; Cosyntropin Stimulation
Included Tests:  Baseline Cortisol; 30 minute Cortisol; 60 minute Cortisol
CPT Coding: 82533 x 3

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