Adrenocorticotropic Hormone Stimulation Test

Last Modified: 1/8/2020 7:20:16 AM

Medical Necessity Documentation:  
Client Notes:

Synthetic ACTH Injections are performed at Parkview Randallia Hospital Infusion Center Only. 

Outpatients - To schedule please contact Parkview Infusion Center (2200 Randallia 2nd Floor) to schedule call 373-4585

Patient Preparation:  
Specimen Requirements:

1.0 mL Serum in a SST Gold Top Tube - One for each timed draw

Collection Instructions:
  1. A base line level Cortisol to be drawn.
  2. Within 30 minutes of baseline being drawn, the patient is to be given a 250-uG dose of synthetic ACTH, Cortrosyn, IM.
  3. A second Cortisol to be drawn one-half hour after this dose is given.
  4. A third Cortisol to be drawn one hour after the dose is given

1. Base Line Cortisol - 8:00 A.M.
2. ACTH Dose - 8:05 A.M. 
3. One-Half Hour Cortisol - 8:35 A.M 
4. One Hour Cortisol - 9:05 A.M.
Above is just an Example of time frames this testing can be started any time (not limited to 8am) 

Minimum Volume: 0.5 mL
Transport & Storage: Temperature/Stability: 48 hours Refrigerated
Reference Range:
No reference range established
Critical Ranges:  
Test Comments:
A normal increase of at least 7 UG/DL of Cortisol is expected for a short ACTH stimulation test.
Methodology: Chemiluminscence
Clinical Significance: Method for testing the adrenal reserve to rule out Addison Disease
Custom Panel: No


Days Performed: Sunday, Monday, Tuesday, Wednesday, Thursday, Friday, Saturday
Sites Performed: Parkview Regional Medical Center
PHL Test Code: ACTHS
EPIC Test Code: LAB711
Alternate Test Names: ACTH Stimulation Test; Addison Disease Testing; Cortrosyn Stimulation; Cosyntropin; Cosyntropin Stimulation
Included Tests:  Baseline Cortisol; 30 minute Cortisol; 60 minute Cortisol
CPT Coding: 82533 x 3

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