FISH, APL, RARA BA

Overview

  • EPIC Code:
  • LAB3071
  • Soft Test Code:
  • AM2F
  • Send Out Test Code:
  • 16665
Alternate Names
  • AML M3, RARA-BA
  • FISH AML M3
  • FISH, AML M3, RARA Breakapart
  • Translocation 15,17
Clinical Significance

Fluorescence in situ hybridization (FISH) to detect rearrangements of the RARA region of chromosome 17 using a dual color breakapart probe.


Specimen Collection & Preparation

Client Notes

If adding to an exsisting Oncology Chromosome Test, then specimen may not be need please contact the Parkview Health Laboratories at 266-1500 (option 1)

Clinical history and reason for referral are required with test order. Prior therapy and transplant history should be provided with test order. 


Specimen Requirements

3.0 mL Bone Marrow in a Green Top Tube - Na Heparin


Transport And Storage

Ambient (transport)

Specimen viability decreases during transit. Send specimen to testing lab for viability determination. DO NOT FREEZE. DO NOT REJECT.


Collection Instructions

 


Minimum Volume

1.0 mL Bone Marrow


Neonatal Volume

Clinical Interpretation

Reference Range:

Refer to Interpretive Results


Test Comments:

If results are not possible, the test order may be canceled and replaced by code 39650 - Cytogenetics Communication.


Methodology:
  • Fluorescence in situ Hybridization (FISH)
Clinical Significance

Fluorescence in situ hybridization (FISH) to detect rearrangements of the RARA region of chromosome 17 using a dual color breakapart probe.


Production Schedule

Sites Performed
  • Quest - Chantilly
Days Performed
Monday
Tuesday
Wednesday
Thursday
Departments
  • Sendouts - Clinical
Turn Around Time

5 to 6 days


Coding & Compliance

CDM

00918050, 00918051


CPT Coding

88271 x2, 88275