Cortisol, Free

Last Modified: 2/20/2019 3:36:21 PM

Medical Necessity Documentation:  
Client Notes:  
Patient Preparation:

Patient should discontinue taking Biotin, Vitamin B7, or Vitamin H 48 hours before getting blood drawn.

Specimen Requirements: 2.0 mL  Serum from a Red Top Tube in a Plastic Vial
Collection Instructions:  
Minimum Volume: 0.7 mL
Transport & Storage: Temperature/Stability: 4 hours Ambient
7 days Refrigerated (Transport)
2 years Frozen
Rejection Criteria: Gross hemolysis • Received room temperature • Serum Separator Tube (SST ®)
Reference Range:
8:00 A.M.-10:00 A.M. 0.07-0.93 µg/dL
4:00 P.M.-6:00 P.M. 0.04-0.45 µg/dL
10:00 P.M.-11:00 P.M. 0.04-0.35 µg/dL
Critical Ranges:  
Test Comments: Patients taking vitamin supplements containing high doses of biotin (>5 mg/day) may have falsely increased test results generated.
Methodology: Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS) • Equilibrium Dialysis
Clinical Significance:  Free cortisol is useful in the detection of patients with Cushing's syndrome for whom free cortisol concentrations are elevated.
Custom Panel: No


Turn Around Time: 8 Days
Days Performed: Sunday, Wednesday
Sites Performed: Quest - Chantilly to San Juan Capistrano
PHL Test Code: CORF
EPIC Test Code: LAB520
Send Out Test Code: 36423
Alternate Test Names: Cortisol Free; Cortisol, Free, LC/MS/MS; Free Cortisol
Included Tests:  
CPT Coding: 82530

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