Levetiracetam

Last Modified: 10/27/2022 2:10:40 PM


Medical Necessity Documentation:  
Client Notes: If Brivaracetam has been prescribed, order Levetiracetam by GC/MS.
Patient Preparation:
Specimen Requirements: 1.0 mL Serum from a Red Top Tube in a Plastic Vial
Collection Instructions: Collect as a trough just prior to next dose

Optimum Time to Collect Sample:
0.5 to 1 hour pre-oral dose, trough at steady state (2 weeks after onset of treatment).
Minimum Volume: 0.5 mL
Transport & Storage: Temperature/Stability: 7 days Ambient (Transport)
21 days Refrigerated
30 days Frozen

Avoid Freeze/Thaw cycles
Rejection Criteria: Serum Separator Tube (SST®) • Specimens collected in any gel barrier tubes • Unspun red-top tube
Reference Range:

6.0-46.0 mcg/mL

Critical Ranges:  
Test Comments:  
Methodology: Immunoassay
Clinical Significance: LEV is currently used as an anti-epileptic drug for the treatment of adult partial seizures particularly as an add-on therapy for refractory patients. It also has potential for other anxiety and cognitive disturbances.
Documentation:  
Custom Panel: No

PRODUCTION SCHEDULE

Turn Around Time: 2 to 3 days
Days Performed: Monday, Tuesday, Wednesday, Thursday, Friday, Saturday
Sites Performed: Quest - Chantilly
PHL Test Code: KEPPR
EPIC Test Code: LAB477
Send Out Test Code: 36330
Alternate Test Names: Keppra; Levetiracetam (Keppra)
Included Tests:  
CPT Coding: 80177

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