DNA (ds) Antibody, Crithidia with Reflex

Overview

  • EPIC Code:
  • LAB2941
  • Soft Test Code:
  • DNADR
  • Send Out Test Code:
  • 37092
Alternate Names
  • Crithidia Luciliae Substrate Assay
  • DNA (ds) Antibody, Crithidia IFA with Reflex to Ti
  • DNA Ab, Crithidia w/ Reflex Titer
Clinical Significance

dsDNA Antibody is detected in patients with active systemic lupus erythematosus (SLE) and approximately 20% of patients with mixed connective tissue disease.


Specimen Collection & Preparation

Patient Preparation

Overnight Fasting is preferred


Specimen Requirements:

-OR-

1.0 mL Serum from a Red Top Tube in a Plastic Vial
Minimum Volume:
0.5 mL Serum*

* This volume does not allow for repeat testing

Transport and Storage:
  • Ambient (18-24°C): 7 Days
  • Refrigerated (2-8°C): 16 Days
  • Frozen (-20° C or colder): 35 Days

Clinical Interpretation

Reference Range:

Negative


Test Comments:

If the DNA (ds) Antibody Screen is positive, DNA (ds) Antibody Titer will be performed at an additional charge (CPT code(s): 86256).


Methodology:
  • Immunofluorescence Assay (IFA)
Clinical Significance

dsDNA Antibody is detected in patients with active systemic lupus erythematosus (SLE) and approximately 20% of patients with mixed connective tissue disease.


Production Schedule

Sites Performed
  • Quest - Chantilly to San Juan Capistrano
Days Performed
Monday
Wednesday
Thursday
Friday
Saturday
Departments
  • Sendouts - Clinical
Turn Around Time

1 to 4 days


Coding & Compliance

CDM

00913333


CPT Coding

86255