This test is useful to evaluate a prolonged aPTT. The second most common form of hemophilia is caused by deficiency of factor IX. Hemophilia B is an x-linked disorder affecting between 1 in 25,000 to 30,000 males.
1.0 mL platelet poor plasma from a Blue Top Tube - 3.2% Na Citrate in a Plastic Vial
Unacceptable Ambient
Unacceptable Refigerated
14 days Frozen
Centrifuge light blue-top tube for 15 minutes at approximately 1500 x g within 60 minutes of collection. Using a plastic pipette, remove plasma, taking care to avoid WBCs/platelet buffy layer and place into a plastic vial. Centrifuge a second time and transfer platelet-poor plasma into a new plastic vial. Plasma must be free of platelets (< 10,000/uL). Freeze immediately and ship on dry ice.
0.5 mL Platelet Poor Plasma
60 -160% of normal
This test is useful to evaluate a prolonged aPTT. The second most common form of hemophilia is caused by deficiency of factor IX. Hemophilia B is an x-linked disorder affecting between 1 in 25,000 to 30,000 males.
Limitations: Expected impact by therapeutic levels (potential interference depends upon drug concentration): Warfarin: Decrease; Heparin (UFH or LMWH): no effect to inhibitor pattern; Dabigatran or Argatroban (Thrombin Inhibitors): no effect to inhibitor pattern; Rivaroxaban or Apixaban (Factor Xa Inhibitors): no effect to inhibitor pattern.
5 to 7 days
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