Amylase Isoenzymes with Reflex to Macroamylase

Last Modified: 5/7/2019 7:00:47 AM

Specimen Requirements: 2.0 mL Serum from a Red Top Tube in a Plastic Vial
Minimum Volume: 1.0 mL Serum
Transport & Storage: Temperature/Stability: Unacceptable Ambient
30 days Refrigerated
30 days Frozen
Rejection Criteria: Hemolysis
Reference Range:

Amylase 21-101 U/L
Pancreatic Isoenzyme 16-46 U/L
Salivary Isoenzymes 4-61 U/L

Test Comments: If Amylase Isoenzymes are >115 U/L, Macroamylase will be performed at an additional charge (CPT code(s): 82150
Methodology: Polyethylene Glycol Precipitation
Clinical Significance: Amylase is produced primarily in the pancreas and salivary glands. Isoenzymes may be used to determine the source of an elevated amylase concentration. Macroamylase is a laboratory and not a clinical entity. Amylase can complex with immunoglobulins or other high molecular weight proteins and serum amylase will appear falsely elevated. No clinical symptoms are associated with macroamylasemia.
Documentation: Limitations: Oxalate, citrate, and lipemic sera can decrease results
Custom Panel: No


Turn Around Time: 1 to 2 days
Days Performed: Monday, Tuesday, Wednesday, Thursday, Friday
Sites Performed: Quest - Chantilly
PHL Test Code: MSOT
EPIC Test Code:
Send Out Test Code: 36187
Alternate Test Names: Salivary Amylase
Included Tests: Amylase, Pancreatic Isoenzyme, Salivary Isoenzymes (calculated)
CPT Coding: 82150

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