Cardio IQ® Lp-PLA2 Activity

Last Modified: 2/15/2019 6:54:09 AM


Patient Preparation: Fasting preferred, but not required
Specimen Requirements:

1.0 mL Serum from a Red Top Tube in a Plastic Vial

Minimum Volume: 0.5 mL Serum
Transport & Storage: Temperature/Stability: 28 days Ambient
28 days Refrigerated
42 days Frozen
Rejection Criteria: Hemolysis • Moderate to grossly lipemic • Moderate to grossly icteric
Reference Range:
Females 50-133 nmol/min/mL
Males 70-153 nmol/min/mL
Methodology: Enzymatic Assay (EZA)
Clinical Significance: Lipoprotein-associated phospholipase A2 (Lp-PLA2), also known as platelet activating factor Acetylhydrolase, is an inflammatory enzyme that circulates bound mainly to low density lipoproteins and has been found to be localized and enriched in atherosclerotic plaques. In multiple clinical trials, Lp-PLA2 activity has been shown to be an independent predictor of coronary heart disease and stroke in the general population. Measurement of Lp-PLA2 may be used along with traditional cardiovascular risk factor measures for identifying individuals at higher risk of cardiovascular disease events. Clinical management may include beginning or intensifying risk reduction strategies. The activity assay is an enzyme assay run on an automated chemistry platform.
Custom Panel: No

PRODUCTION SCHEDULE

Turn Around Time: 2 to 3 days
Days Performed: Monday, Tuesday, Wednesday, Thursday, Friday, Saturday
Sites Performed: Quest - Chantilly to San Juan Capistrano
PHL Test Code: LPPLA
EPIC Test Code: LAB3106
Send Out Test Code: 94218
Alternate Test Names: CARDIO IQ LP-PLA2 ACTIVITY; PAF-AH
CPT Coding: 83698

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