Antithrombin III Activity

Last Modified: 7/29/2020 11:50:52 AM

Medical Necessity Documentation:  
Client Notes:  
Patient Preparation:  
Specimen Requirements:

1.0 mL Plasma from a Blue Top Tube - 3.2 % Sodium Citrate in a Plastic Vial

Collection Instructions:
Draw blood in light blue-top tube containing 3.2% sodium citrate, and mix gently by inverting 3-4 times. 
Centrifuge 15 minutes at 1500 x g within 1 hour of collection. 
Using a plastic pipette, remove plasma, taking care to avoid the WBC/platelet buffy layer and place into a plastic vial. 
Centrifuge a second time and transfer platelet-poor plasma into a new plastic vial(s). 
Freeze immediately and transport on dry ice.

Avoid Hemolysis 

Avoid presence of microclots
Minimum Volume: 0.5 mL
Transport & Storage: Temperature/Stability: 1 month Frozen
Reference Range: 1 day to 1 month: 41-108 % normal
31 days to 2 months: 50-120 % normal
3 to 5 months: 73-120 % normal
≥ 6 months: 80-135 % normal
Critical Ranges:  
Test Comments:  
Methodology: Chromogenic Substrate
Clinical Significance:  
Custom Panel: No


Turn Around Time: 2 to 5 days
Days Performed: Monday, Tuesday, Wednesday, Thursday, Friday
Sites Performed: Quest - Chantilly
PHL Test Code: THRM3
EPIC Test Code: LAB311
Send Out Test Code: 216
Included Tests:  
CPT Coding: 85300

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