Apolipoprotein B

Overview

  • EPIC Code:
  • IMO102
  • Soft Test Code:
  • APOL
  • Send Out Test Code:
  • 5224
Alternate Names
  • Apo B
Clinical Significance

Apolipoprotein B (APO B) has been reported to be a powerful indicator of CAD. In some patients with CAD, APO B is elevated even in the presence of normal LDL cholesterol


Specimen Collection & Preparation

Patient Preparation

Fasting 12 hours


Specimen Requirements:

-OR-

1.0 mL Serum from a Red Top Tube in a Plastic Vial
Minimum Volume:
0.5 mL Serum *

* This volume does not allow for repeat testing

Rejection Criteria:

Grossly lipemic


Transport and Storage:
  • Ambient (18-24°C): 7 Days

    Transport 

  • Refrigerated (2-8°C): 7 Days
  • Frozen (-20° C or colder): 30 Days

Clinical Interpretation

Reference Range:

<90 mg/dL

Risk Category

 
Optimal <90 mg/dL
Moderate 90-129 mg/dL
High ≥130 mg/dL

 


Test Comments:

A desirable treatment target may be <80 mg/dL or lower depending on the risk category of the patient including patients on lipid lowering therapies, patients with ASCVD, diabetes with >1 risk factors, Stage 3 or greater CKD with albuminuria, or heterozygous familial hypercholesterolemia. ApoB relative risk category cut points are based on AACE/ACE and ACC/AHA recommendations (Grundy SM, et al. 2019. doi:10.1016/j.jacc.2018.11.002; Handelsman Y, et al. 2020. doi:10.4158/CS-2020-0490).


Methodology:
  • Immunoassay (IA)
Clinical Significance

Apolipoprotein B (APO B) has been reported to be a powerful indicator of CAD. In some patients with CAD, APO B is elevated even in the presence of normal LDL cholesterol


Production Schedule

Sites Performed
  • Quest - Chantilly to San Juan Capistrano
Days Performed
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Departments
  • Sendouts - Clinical
Turn Around Time

2 to 5 days


Coding & Compliance

CDM

00910524


CPT Coding

82172