Doxepin

Overview

  • EPIC Code:
  • MISC
  • Soft Test Code:
  • MSOT
  • Send Out Test Code:
  • 826
Alternate Names
  • Adapin®
  • Desmethydoxepin
  • Desmethyldesipramine
  • Doxepin, Trough
  • Nordaxepin
  • Sinequan
  • Sinequan®
  • Zonalon
Included Tests

Doxepine; Nordoxepin (Desmethyldoxepin)


Clinical Significance

Doxepin is a tricyclic antidepressant. Therapeutic drug levels are monitored to assist the physician assessing therapeutic response and to avoid toxicity.


Specimen Collection & Preparation

Specimen Requirements

3.0 mL Serum from a Red Top Tube in a Plastic Vial


Alternate Specimen

3.0 mL Plasma from 2 Lavender Top Tubes - EDTA in a Plastic Vial 
or 
3.0 mL Plasma from a Green Top Tube - Li Heparin in a Plastic Vial 
or 
3.0 mL Plasma from a Green Top Tube - Na Heparin in a Plastic Vial


TransportAndStorage

5 days Ambient (Transport)
7 days Refrigerated
30 days Frozen


Collection Instructions

Collect at steady-state trough concentration Specimen should be collected > 12 hours after dose

Centrifuge and separate from cells immediately


Minimum Volume

1.5 mL Serum


Neonatal Volumne

Clinical Interpretation

Reference Range:

Total 110-250 mcg/L


Methodology:
  • Chromatography / Mass Spectrometry

Clinical Significance

Doxepin is a tricyclic antidepressant. Therapeutic drug levels are monitored to assist the physician assessing therapeutic response and to avoid toxicity.


Production Schedule

Sites Performed
  • Quest - Chantilly
Days Performed
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Departments
  • Sendouts - Miscellaneous
Turn Around Time

1 to 2 days


Coding & Compliance

CDM

00913333


CPT Coding

80335