Histoplasma Antibody Panel

Overview

  • EPIC Code:
  • MISC
  • Soft Test Code:
  • MSOT
  • Send Out Test Code:
  • 37094
Alternate Names
  • Histoplasma Antibody Panel, CF and ID
  • Histoplasma Mycelial Yeast
Included Tests

Histoplasma Antibody, Complement Fixation, Serum; Histoplasma Antibody, Immunodiffusion, Serum


Clinical Significance

Histoplasmosis, caused by infection by H. capsulatum, is usually asymptomatic or mild. Some patients develop chronic pulmonary histoplasmosis or acute disseminated histoplasmosis that is often life-threatening. Immunodiffusion testing detects antibodies in approximately 70% of patients with histoplasmosis, and complement fixation testing detects antibodies in approximately 90% of patients.


Specimen Collection & Preparation

Specimen Requirements

2.0 mL Serum in a SST Gold Top Tube


Transport And Storage

7 days Ambient
14 days Refrigerated
30 days Frozen


Collection Instructions

 


Minimum Volume

0.6 mL Serum


Neonatal Volume

Clinical Interpretation

Reference Range:

Histoplasma Antibody, CF   
      Yeast Phase Ab       <1:8  
      Mycelial Phase Ab   <1:8

Histoplasma Antibody, ID  Negative


Methodology:
  • Complement Fixation (CF)
  • Immunodiffusion (ID)
Clinical Significance

Histoplasmosis, caused by infection by H. capsulatum, is usually asymptomatic or mild. Some patients develop chronic pulmonary histoplasmosis or acute disseminated histoplasmosis that is often life-threatening. Immunodiffusion testing detects antibodies in approximately 70% of patients with histoplasmosis, and complement fixation testing detects antibodies in approximately 90% of patients.


Production Schedule

Sites Performed
  • Quest - Chantilly
Days Performed
Tuesday
Wednesday
Thursday
Friday
Saturday
Departments
  • Sendouts - Clinical
Turn Around Time

2 to 5 days


Coding & Compliance

CDM

00913333


CPT Coding

86698 (x3)