Last Modified:
11/1/2022 7:01:52 AM
Medical Necessity Documentation:
Client Notes:
Patient Preparation:
Specimen Requirements:
2.0 mL Serum in a SST Gold Top Tube
Collection Instructions:
Minimum Volume:
0.6 mL Serum
Transport & Storage: Temperature/Stability:
7 days Ambient
14 days Refrigerated
30 days Frozen
Rejection Criteria:
Gross hemolysis; grossly icteric; grossly lipemic
Reference Range:
Histoplasma Antibody, CF
Yeast Phase Ab <1:8
Mycelial Phase Ab <1:8
Histoplasma Antibody, ID Negative
Critical Ranges:
Test Comments:
Methodology:
Complement Fixation (CF) • Immunodiffusion (ID)
Clinical Significance:
Histoplasmosis, caused by infection by H. capsulatum, is usually asymptomatic or mild. Some patients develop chronic pulmonary histoplasmosis or acute disseminated histoplasmosis that is often life-threatening. Immunodiffusion testing detects antibodies in approximately 70% of patients with histoplasmosis, and complement fixation testing detects antibodies in approximately 90% of patients.
Documentation:
Custom Panel:
No
PRODUCTION SCHEDULE
Turn Around Time:
2 to 5 days
Days Performed:
Tuesday, Wednesday, Thursday, Friday, Saturday
Sites Performed:
Quest - Chantilly
PHL Test Code:
MSOT
EPIC Test Code:
MISC
Send Out Test Code:
37094
Alternate Test Names:
Histoplasma Antibody Panel, CF and ID ; Histoplasma Mycelial Yeast
Included Tests:
Histoplasma Antibody, Complement Fixation, Serum; Histoplasma Antibody, Immunodiffusion, Serum
CPT Coding:
86698 (x3)
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