Insulin - Like Growth Factor I

Last Modified: 3/27/2019 4:25:40 PM

Medical Necessity Documentation:  
Client Notes:  
Patient Preparation:  
Specimen Requirements: 1.0 mL Serum from a Red Top Tube in a Plastic Vial
Collection Instructions: Allow blood to clot (10-15 minutes) at ambient temperature
Separate serum from cells 
Freeze Serum
Minimum Volume: 0.5 mL Serum
Transport & Storage: Temperature/Stability:

48 hours Ambient
5 days Refrigerated
7 days Frozen

Rejection Criteria: Gross hemolysis; Gross lipemia; Slightly, moderately, and grossly icteric samples; Samples received at room temperature; Frozen glass tubes.
Reference Range:
Refer to Interpretive Results
Critical Ranges:  
Test Comments:  
Methodology: LC/MS
Clinical Significance: Insulin-like growth factor I (IGF-I, or somatomedin C), a protein involved in stimulating somatic growth, is regulated principally by growth hormone (GH) and nutritional intake. IGF-I is transported in serum by several proteins; this helps maintain relatively high IGF-I plasma levels and minimizes fluctuations in serum IGF-I concentrations.

Measuring IGF-I is useful in several growth-related disorders. Dwarfism caused by deficiency of growth hormone
(hypopituitarism) results in decreased serum levels of IGF-I, while acromegaly (growth hormone excess) results in
elevated levels of IGF-I. IGF-I measurements are also helpful in assessing nutritional status; levels are reduced in undernutrition and restored with a proper diet.
Custom Panel: No


Turn Around Time: 5 to 8 days
Days Performed: Monday, Tuesday, Wednesday, Thursday, Friday
Sites Performed: Quest - Chantilly to San Juan Capistrano
PHL Test Code: SOMA1
EPIC Test Code: LAB526
Send Out Test Code: 16293 / S51997
Alternate Test Names: IGF-1; IGF-I, Electrochemiluminescence; Insulin Growth Factor; Somatomedin C
Included Tests:  
CPT Coding: 84305

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