Last Modified:
3/27/2019 4:25:40 PM
Medical Necessity Documentation:
Client Notes:
Patient Preparation:
Specimen Requirements:
1.0 mL Serum from a Red Top Tube in a Plastic Vial
Collection Instructions:
Allow blood to clot (10-15 minutes) at ambient temperature
Separate serum from cells
Freeze Serum
Minimum Volume:
0.5 mL Serum
Transport & Storage: Temperature/Stability:
48 hours Ambient
5 days Refrigerated
7 days Frozen
Rejection Criteria:
Gross hemolysis; Gross lipemia; Slightly, moderately, and grossly icteric samples; Samples received at room temperature; Frozen glass tubes.
Reference Range:
Refer to Interpretive Results
Critical Ranges:
Test Comments:
Methodology:
LC/MS
Clinical Significance:
Insulin-like growth factor I (IGF-I, or somatomedin C), a protein involved in stimulating somatic growth, is regulated principally by growth hormone (GH) and nutritional intake. IGF-I is transported in serum by several proteins; this helps maintain relatively high IGF-I plasma levels and minimizes fluctuations in serum IGF-I concentrations.
Measuring IGF-I is useful in several growth-related disorders. Dwarfism caused by deficiency of growth hormone
(hypopituitarism) results in decreased serum levels of IGF-I, while acromegaly (growth hormone excess) results in
elevated levels of IGF-I. IGF-I measurements are also helpful in assessing nutritional status; levels are reduced in undernutrition and restored with a proper diet.
Documentation:
Custom Panel:
No
PRODUCTION SCHEDULE
Turn Around Time:
5 to 8 days
Days Performed:
Monday, Tuesday, Wednesday, Thursday, Friday
Sites Performed:
Quest - Chantilly to San Juan Capistrano
PHL Test Code:
SOMA1
EPIC Test Code:
LAB526
Send Out Test Code:
16293 / S51997
Alternate Test Names:
IGF-1; IGF-I, Electrochemiluminescence; Insulin Growth Factor; Somatomedin C
Included Tests:
CPT Coding:
84305
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