Multiple Sclerosis Panel 2

Overview

  • EPIC Code:
  • IMO101
  • Soft Test Code:
  • MSPN2
  • Send Out Test Code:
  • 7085
Alternate Names
  • MS
  • MS Panel 2
  • MS Profile 2
  • MSPRO
  • Multiple Sclerosis Evaluation
  • Multiple Sclerosis Panel 2
  • Multiple Sclerosis Profile
Included Tests

Albumin (CSF and Serum); IgG (CSF and Serum); IgG Synthesis Rate/Index CSF; Myelin Basic Protein; Oligoclonal Bands CSF.


Clinical Significance

Patients with Multiple Sclerosis (MS) have multiple, scarred areas of the brain. Symptoms can initially be mild but typically lead to relapsing or progressive incapacitating neuromotor dysfunction.


Specimen Collection & Preparation

Specimen Requirements

4.0 mL CSF in a #4 CSF Collection Sterile Plastic Vial
and
2.0 mL Serum from a Red Top Tube in a Plastic Vial


Transport And Storage

8 hours Ambient (Not accepted)
5 days Refrigerated
14 days Frozen

Refrigerated CSF at 2-8°C in sterile, plastic CSF vials, and send refrigerated (Cold Packs) to lab
or 
Freeze CSF specimens at -20°C and send frozen to the lab on dry ice.


Collection Instructions

Serum and CSF samples should be drawn on same day for most reliable results

If multiple testing is required for the CSF specimen, please list the testing priorities on the order

It is preferred that the collection date and time be the same for both CSF and Serum; however it is acceptable for them to be drawn within 48 hours of each other. CSF must be crystalline and clear.

Blood contamination and hemolysis may interfere with results. Submitting 4th lumbar puncture collection tube minimizes blood contamination.


Minimum Volume

1.0 mL Serum & 1.8 mL CSF


Neonatal Volume

Clinical Interpretation

Reference Range:

See interpretive report


Methodology:
  • Isoelectric Focusing (IEF)
  • Nephelometry
  • Radioimmunoassay (RIA)
Clinical Significance

Patients with Multiple Sclerosis (MS) have multiple, scarred areas of the brain. Symptoms can initially be mild but typically lead to relapsing or progressive incapacitating neuromotor dysfunction.


Documentation

 Useful in the diagnosis of  Multiple Sclerosis.


Production Schedule

Sites Performed
  • Quest - Chantilly
Days Performed
Monday
Tuesday
Wednesday
Thursday
Friday
Departments
  • Sendouts - Clinical
Turn Around Time

4 to 5 days


Coding & Compliance

CPT Coding

82040, 82042, 82784 (x2), 83873, 83916