Last Modified:
8/12/2021 5:41:23 AM
Medical Necessity Documentation:
Client Notes:
Patient Preparation:
Specimen Requirements:
1.0 mL Serum in a SST Gold Top Tube
Collection Instructions:
Centrifuge and separate from cells within one hour of collection
Minimum Volume:
0.5 mL
Transport & Storage: Temperature/Stability:
7 days Ambient
14 days Refrigerated (Preferred)
30 days Frozen
Avoid Thaw/Freeze Cycles
Rejection Criteria:
Gross hemolysis; grossly icteric; grossly lipemic
Reference Range:
Yeast Phase Ab |
<1:8 |
Mycelial Phase Ab |
<1:8 |
Critical Ranges:
Test Comments:
Clinical interpretation of complement fixation test results requires comparison of an acute serum sample to a convalescent serum sample. The convalescent serum sample should be collected 2-3 weeks later.
Methodology:
Complement Fixation
Clinical Significance:
Histoplasma Antibody, Complement Fixation, Serum - This test is used for the diagnosis and prognosis of histoplasma infections.
Titers ≥1:32 are highly suggestive of H. capsulatum infection. The CF test is more frequently positive with sera from chronic active pulmonary histoplasmosis than sera from primary active pulmonary disease.
Documentation:
Custom Panel:
No
PRODUCTION SCHEDULE
Turn Around Time:
2 to 5 days
Days Performed:
Tuesday, Wednesday, Thursday, Friday
Sites Performed:
Quest - Chantilly
PHL Test Code:
HISTO
EPIC Test Code:
IMO413
Send Out Test Code:
938
Alternate Test Names:
Histoplasma Antibody, CF; Histoplasma Antibody, Complement Fixation; Histoplasma Antibody, Complement Fixation, Serum; Histoplasma Mycelial Yeast
Included Tests:
Mycelial Phase Antibody; Yeast Phase Antibody;
CPT Coding:
86698 x 2
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